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Lauren Black
Assistant Professor, Department of Biomedical Engineering
Education
2006 Ph.D., Boston University, Biomedical Engineering
2003 M.S., Boston University, Biomedical Engineering
2000 B.S., University of Cincinnati, Aerospace Engineering
Honors and Awards
- Pathway to Independence (K99/ R00) Grantee from the National Heart, Lung and Blood Institute of the National Institutes of Health (NIH)
- Individual Postdoctoral Fellowship (F32) from the National Heart, Lung and Blood Institute of the National Institutes of Health (NIH)
Research Interests
Dr. Black's research interests lie in understanding the biophysical signaling
mechanisms responsible for the development of healthy and diseased myocardium
inclusive of mechanical stress/strain, electrical stimulation, and cell-cell/
cell-matrix interactions. The ultimate goal of his research is to design and
develop new methods for repairing diseased or damaged myocardium. The work in
his lab spans the following areas:
- The use of novel methods, such as whole organ decellularization, to
study the role that the local extracellular environment (matrix stiffness,
morphology and composition) plays in the progression of myocardial disease
and how it relates to the potential effectiveness of cell therapy based
methods of cardiac repair.
- Investigation into the physicochemical signaling mechanisms (growth
factors, electrical stimulation, mechanical stimulation) responsible for the
development of healthy myocardium from cardiac precursor or stem/ progenitor
cells.
- The design, development and evaluation of new methods for cardiac repair
following myocardial infarction (“heart attack”) and heart failure,
inclusive of tissue engineered ventricular myocardium created in vitro
for implantation in vivo.
Service Memberships
- Biomedical Engineering Society
- American Heart Association
- Tissue Engineering and Regenerative Medicine International Society
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