Seminar Series |
Science & Technology Center
Medford, MA 02155
> Curriculum Vitae
Associate Professor, Department of Biomedical Engineering
2006 Ph.D., Boston University, Biomedical Engineering
2003 M.S., Boston University, Biomedical Engineering
2000 B.S., University of Cincinnati, Aerospace Engineering
Honors and Awards
- Individual Postdoctoral Fellowship (F32) from the National Heart,
Lung and Blood Institute of the National Institutes of Health (NIH) (2007)
- Pathway to Independence (K99/ R00) Grantee from the National Heart,
Lung and Blood Institute of the National Institutes of Health (NIH) (2009)
- Faculty Research Awards Council grant (2011)
- Tufts University Catalyst Award for a research project with Gordon
Huggins and Phil Hinds both of Tufts Medical Center (2012)
Dr. Black's research interests lie in understanding the biophysical
signaling mechanisms responsible for the development of healthy and
diseased myocardium inclusive of mechanical stress/strain, electrical
stimulation, and cell-cell/ cell-matrix interactions. The ultimate goal
of his research is to design and develop new methods for repairing diseased
or damaged myocardium. The work in his lab spans the following areas:
- The use of novel methods, such as whole organ decellularization,
to study the role that the local extracellular environment (matrix
stiffness, morphology and composition) plays in the progression of
myocardial disease and how it relates to the potential effectiveness
of cell therapy based methods of cardiac repair.
- Investigation into the physicochemical signaling mechanisms
(growth factors, electrical stimulation, mechanical stimulation)
responsible for the development of healthy myocardium from cardiac
precursor or stem/ progenitor cells.
- The design, development and evaluation of new methods for
cardiac repair following myocardial infarction ("heart attack")
and heart failure, inclusive of tissue engineered ventricular
myocardium created in vitro for implantation in vivo.
- The role of alterations in the mechanical environment in the
development and progression of diseases like calcific aortic valve
disease and hypoplastic left heart syndrome (HLHS).
- Biomedical Engineering Society
- American Heart Association
- Tissue Engineering and Regenerative Medicine International Society
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