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Science & Technology Center
4 Colby Street
Tufts University
Medford, MA 02155

Tel: 617-627-0447
Fax: 617-627-3231
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Barbara Brodsky
Research Professor, Department of Biomedical Engineering

Education

1970, Ph.D., Harvard University, Biophysics
1964, B.A. Brandeis University, Physics

Honors and Awards

  • Editorial Board, Journal of Biological Chemistry
  • Editor, Newsletter International Society of Matrix Biology
  • AAAS Fellow
  • Helen Hay Whitney Postdoctoral Fellowship
  • NIH Research Career Development Award
  • Thomas Alva Edison Patent Award
  • Richard Harvey Teaching Award
  • Member, International Society of Matrix Biology Council

Research Interests

Barbara Brodsky's research, funded by NIH grants, focuses on collagen, an extracellular matrix component critical for tissue structure, mechanical properties, cell adhesion and receptor mediated cell signaling. Her laboratory characterizes structural features of collagen using model peptides and a recently developed recombinant bacterial collagen. The recombinant molecules serve as an excellent model system for defining collagen binding sites and the effects of collagen mutations, while the peptides allow definition of high resolution features at biologically important sites. Research is currently underway to clarify the pathway from human collagen mutations to hereditary bone disorders, kidney disease, and vascular pathology. Studies are being initiated to utilize the recombinant collagen system as a scaffold to promote bone generation by human stem cells and for the development of biomaterials.

Biography

Barbara Brodsky earned her B.A. in physics from Brandeis University in 1964 and her Ph.D. in biophysics from Harvard University in 1970, after which she carried out postdoctoral research as a Helen Hay Whitney Fellow at NIH and Oxford University, UK. From 1975-2010, she served on the faculty of the department of biochemistry at Robert Wood Johnson Medical School, affiliated with Rutgers University, ultimately achieving the rank of Professor and position of Deputy Chair while maintaining continuous NIH funding for her collagen research. In 2010, she joined the Tufts Department of Biomedical Engineering as a Research Professor.

Professional Positions

1975 - 2010 Professor, UMDNJ-Rutgers Medical School, Biophysics, New Jersey
2004 - 2005 Visiting Researcher, European Bioinformatics Institute, Hinxton, England
1984 - 1985 Visiting Researcher, Brandeis University, Structural Biology, Waltham, Massachusetts

Service Memberships

  • American Society of Biochemistry and Molecular Biology
  • American Chemical Society
  • Biophysical Society
  • Protein Society
  • International Society of Matrix Biology