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Education1999 Ph.D., University of Rochester, Rochester NY, Biophysics
1996 M.Sc., University of Rochester, Rochester NY, Biophysics
1993, BA, Dartmouth College, Hanover, NH, Physics
Research InterestsOur lab is interested in the development of new or improved methods to assess different aspects of the normal or diseased development of human tissues that rely on light interactions and are thus non-invasive. In principle, our goal is to identify ways that provide us with biochemical and morphological information about the tissue by using an optical probe instead of using current approaches that rely on excising the tissue and processing it. Optical methods do not only obviate the need for a biopsy; they enable us to study the same specimen dynamically over time, they do not interfere with the physiology of the subject and they do not suffer from artifacts. This is especially true for the methods that we are particularly interested in that rely entirely on endogenous sources of contrast.
The main application areas of research in the lab include tissue engineering and cancer diagnostics. We expect that the tools we develop will be useful in developing novel diagnostics that can be used to assess tissue function during normal and diseased development as well as in response to treatments. Specific areas of interest include:
BiographyIrene Georgakoudi has been working on the use of lasers for therapeutic and diagnostic applications since her undergraduate years. She started as a physicist at Dartmouth College and continued her graduate studies in Biophysics at the University of Rochester. Her interests in spectroscopy and spectroscopic imaging using endogenous sources of contrast were founded during her postdoctoral years at the MIT Spectroscopy Lab. After working on the development of fluorescence-based in vivo flow cytometry while an Instructor at the Wellman Laboratories for Photomedicine at Massachusetts General Hospital/Harvard Medical School, she moved to Tufts in 2004. She is the author of several patents on the development and use of spectroscopy and imaging to characterize tissues or to detect specific populations of cells and has published numerous peer reviewed manuscripts, review articles and book chapters in these topics. She is the recipient of a Claflin Distinguished Scholar, an NSF Career, and an American Cancer Society Research Scholar award. She has served on the Board of Directors of the Optical Society of America, and is the Director of the Tufts Advanced Microscopic Imaging Center (TAMIC).
EN 31- Exploring Laser Light
BME 101 - Medical Optics and Lasers
Honors and Awards
2010 Program co-chair, Microscopy, Optical Society of America Meeting on
Biomedical Optics, Miami Beach, FL
Membership in Professional Societies
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