resorbable technology

 

We work on redefining technological components such as optics, electronics, micromechanics, and nanostructures to resorb into the surrounding environment or in living tissue without harmful effects and at programmable timescales. 


This work is inspired by applying tissue engineering paradigms (scaffolds that remodel) to high tech (photonics that are living and remodel) and is based on the early collaboration with the Biopolymer Engineering group here at Tufts in 2006.  The work has since grown to cover multiple contexts and applications embracing ever evolving technological sophistication.


This approach challenges traditional form and function and design metrics that are typical of the technological world where materials are  designed to remain invariant over time.  


This research has important applications in medicine, distributed monitoring, and new bio-functional devices.  Further, the development of functioning technologies based on water-based processes from naturally derived materials has important implications for sustainability, energy efficiency and environmental impact of materials.


RELEVANT PUBLICATIONS


Bioactive silk protein biomaterial systems for optical devices. Biomacromolecules, 2008. 9(4): p. 1214-1220.

A new route for silk. Nature Photonics, 2008. 2(11): p. 641-643

Biocompatible Silk Printed Optical Waveguides. Advanced Materials, 2009. 21(23): p. 2411

Implantable, multifunctional, bioresorbable optics. Proceedings of the National Academy of Sciences of the United States of America, 2012. 109(48): p. 19584-19589

Synthesis and characterization of biocompatible nanodiamond-silk hybrid material. Biomedical Optics Express, 2014. 5(2): p. 596-608.

A Physically Transient Form of Silicon Electronics, Science, 337 (2012) 1640-1644

Fabrication of Silk Microneedles for Controlled-Release Drug Delivery, Adv. Funct. Mater., 22 (2012) 330-335

Materials for Bioresorbable Radio Frequency Electronics. Advanced Materials, 2013. 25(26): p. 3526-3531

Silk-based resorbable electronic devices for remotely controlled therapy and in vivo infection abatement. Proceedings of the National Academy of Sciences of the United States of America, 2014. 111(49): p. 17385-17389

Laser-based three-dimensional multiscale micropatterning of biocompatible hydrogels for customized tissue engineering scaffolds. Proceedings of the National Academy of Sciences of the United States of America, 2015. 112(39): p. 12052-12057

Materials for Programmed, Functional Transformation in Transient Electronic Systems. Advanced Materials, 2015. 27(1): p. 47-52

implantable, dissolvable mirrors

Wireless dissolvable Mg-electronics