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School of Engineering

Emmanuel (Manolis) Tzanakakis

Associate Professor
Chemical and Biological Engineering
Tzanakakis Lab

Emmanuel (Manolis) Tzanakakis

Associate Professor
Chemical and Biological Engineering
Tzanakakis Lab

Phone 617-627-0831
Science and Technology Center, Room 276A
4 Colby Street, Medford, MA
stem cell and tissue engineering

Emmanuel Tzanakakis is an associate professor in the Department of Chemical and Biological Engineering at Tufts University. He earned his Ph.D. in Chemical Engineering from the University of Minnesota. Tzanakakis did his postdoctoral training at the Stem Cell Institute of the University of Minnesota and at the Diabetes Center of the University of California, San Francisco. His laboratory’s research interests are in the area of stem cell engineering, particularly for diabetes and heart disease applications. Implementing a combination of experiment- and computation-based approaches, the overarching goal of his research is the realization of the potential of stem cells in regenerative medicine.

Ph.D., Chemical Engineering, University of Minnesota, 2001
Dipl., Chemical Engineering, Aristotle University of Thessaloniki, 1995
Professional Experience: 

Associate Professor, Department of Chemical and Biological Engineering, Tufts School of Engineering


Associate Professor, Department of Biomedical Engineering, State University of New York at Buffalo


Director, Stem Cell Culture, Banking, and Training Facility, Western New York Stem Cell Culture and Analysis Center


Department of Chemical and Biological Engineering, State University of New York at Buffalo

  • 2010-2014: Associate Professor
  • 2004-2010: Assistant Professor
Research Interests: 

Emmanuel Tzanakakis' research interests include stem cell engineering, stem cell bioprocessing, and multiscale models of stem cell ensembles. Pluripotent stem cells self-renew extensively and give rise to multiple cell types of therapeutic significance. Tzanakakis' laboratory investigates the molecular determinants of stem cell commitment along particular lineages, mainly to heart muscle and pancreatic endocrine insulin-producing cells. Additionally, the lab's efforts concentrate on scalable expansion and differentiation, which are prerequisites for the realization of stem cell-based applications envisioned in regenerative medicine and tissue engineering.

Selected Honors and Awards: 
2006-2008: James D. Watson Investigator Award, New York State Office of Science, Technology, and Academic Research
2003-2005: Juvenile Diabetes Research Foundation Postdoctoral Fellowship
Teaching/Courses Taught: 
ChBE: Applied Numerical Methods for Chemical and Biological Engineering
ChBE: Fundamentals of Chemical Engineering
ChBE: Chemical Plant Design
BME/ChBE: Biological Transport & Kinetics
BME/ChBE: Biosystems Engineering
ChBE: Fluid Mechanics

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