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School of Engineering

Sergio Fantini

Biomedical Engineering
Diffuse Optical Imaging of Tissue Lab

Sergio Fantini

Biomedical Engineering
Diffuse Optical Imaging of Tissue Lab

Phone 617-627-4356
Science and Technology Center, Room 267E
4 Colby Street, Medford, MA
biomedical optics, near-infrared spectroscopy, diffuse optical imaging

Sergio Fantini received his doctoral degree in physics from the University of Florence, Italy, in 1992. His dissertation was based on a Raman scattering study of ceramic superconductors. From 1993 to 1999, Fantini held postdoctoral and faculty appointments at the University of Illinois at Urbana-Champaign, in the Department of Physics. In 1999, he joined Tufts University as an assistant professor and has been one of the inaugural faculty members of the Department of Biomedical Engineering, which was created at Tufts in 2002.

Fantini's research interests lie in the area of biomedical optics, specifically in diffuse near-infrared spectroscopy and the imaging of biological tissues. His research laboratory (the Diffuse Optical Imaging of Tissue Lab, or DOIT Lab) aims to develop noninvasive applications of diffuse optics to assess cerebral perfusion and brain activity, detect breast cancer, monitor response to neoadjuvant chemotherapy, and quantify skeletal muscle oxygenation. Fantini’s research has resulted in eleven patents and about 200 journal and conference proceedings publications. In 2016, he coauthored, with Professor Irving Bigio of Boston University, a textbook titled Quantitative Biomedical Optics. The book was published by Cambridge University Press.

Ph.D., University of Florence, 1992
Professional Experience: 

Department of Biomedical Engineering, Tufts School of Engineering

  • 2006-present: Professor
  • 2003-2006: Associate Professor
  • 2002-2003: Assistant Professor

Tufts School of Engineering

  • 2006-2009: Associate Dean for Graduate Education
  • 2004-2005: Acting Associate Dean

Assistant Professor, Department of Electrical Engineering and Computer Science, Tufts School of Engineering


Department of Physics, University of Illinois—Urbana-Champaign

  • 1996-1999: Research Assistant Professor
  • 1995-1996: Visiting Lecturer
Research Interests: 

Research activities in Sergio Fantini's group include quantitative modeling of light propagation in optically turbid media, the design of optical instrumentation for medical imaging, the development of novel near-infrared spectroscopy and imaging techniques for medical diagnostics, and a number of applications for animal models and human subjects. Specific applications are aimed at functional imaging of the brain, cerebral hemodynamics assessment, diffuse optical mammography, hemoglobin concentration and saturation in skeletal muscles, and quantitative tissue oximetry.

Selected Honors and Awards: 
Fellow, American Institute for Medical and Biological Engineering (AIMBE)
Fellow, The International Society for Optical Engineering (SPIE)
2004: Graduate Student Council's Award for Outstanding Faculty Contribution to Graduate Studies, Tufts University
2001: Outstanding Faculty Award, Tufts University
Professional Memberships: 
American Institute for Medical and Biological Engineering
Biomedical Engineering Society
Optical Society of America
SPIE – The International Society for Optical Engineering
Teaching/Courses Taught: 
BME-141: Analytical Tools for Biomedical Engineering
BME/EE/BIO-131: Principles of Medical Imaging