The Kaplan Lab focuses on biomaterials derived from biopolymer engineering and on tissue engineering and regenerative medicine.
The lab utilizes fibrous proteins from nature (e.g., elastins, silks, collagens, resilins) and bioengineered variants to study structure-function from both fundamental and applied views. The lab has pioneered the study of silk protein-based biomaterials with the emergence of silk as a new option in the degradable polymer field with excellent biocompatibility, new fundamental understanding of control of water to regulate structure and properties, and new tissue-specific outcomes with silk as scaffolding in gel, fiber, film, sponge and dense medical device formats. Recent efforts focus on dynamic protein-based biomaterials utilizing silk-elastin copolymers and on modulating crystallization related to sustained drug delivery.
Tissue engineering uses complex 3D tissue co-culture systems to establish and study 3D human tissues. These systems are used to study diseases associated with brain, intestine, kidney, lung, bone, cornea and skin, including therapeutic screening under acute and chronic exposures. We are also applying tissue engineering methods towards cellular agriculture initiatives for food-related goals.
In addition to graduate and postdoctoral students, we welcome motivated undergraduates who would like to assist with ongoing research projects or engage in independent projects. We look for intelligent, highly motivated, and creative individuals at all levels who are committed to conducting research of the highest quality.
Visit the Department of Biomedical Engineering website for further information on the Graduate Program and
Undergraduate Program. In case of administrative questions please contact Milva Ricci or Keleigh Sanford.
Tel: 617.627.3251   |   Email   |   Directions to Lab