Laboratory Research

In the Lantagne Group, we conduct laboratory, field, and policy implementation-based research to reduce the burden of infectious diseases. Our laboratory work is conducted in the Environmental Sustainability Lab, we conduct research to determine the efficacy of interventions and test methods.

Current Laboratory Projects

Closing the Gap: Action Research on CISUR Interventions in Emergency Response
Sponsor: OFDA

Filling the Gap: Researching CISUR Interventions to Prevent Cholera
Sponsor: R2HC

Laboratory investigations of fouling in membrane filters used for household water treatment in low-income and emergency contexts
Sponsor: Tufts University

Collaboration between Tufts and Kohler of a Novel Ceramic Filter
Sponsor: Kohler

Completed Laboratory Projects

Applied Research on Disinfection of Hands, Surfaces, and Wastewater to Prevent Ongoing Transmission of Ebola
Sponsor: OFDA
Collaborators: University of Brighton and Partners Healthcare

Accuracy, Precision, Cost, and Acceptability of Silver Testing Methods in Ceramic Filter Manufacturing Facilities
Sponsor: Faculty Research Fund of Tufts University

Monitoring for Safe Water Sodium Thiosulfate Experiment
Sponsor: Aquaya

Relationship between E. coli and Vibrio Cholerae in Source Water, Untreated Household Water, and Treated Household Drinking Water in Haiti
Sponsor: Tufts Institute for Innovation
Co-PI: Natalie Capiro


Lyon-Marion B, Mittelman A, Rayner J, Lantagne D, and Pennell K (2018). Impact of chlorination on silver elution from ceramic water filter. Water Research 142:471-479.

Lantagne D, Wolfe M, Gallandat K, and Opryszko M (2018). Determining the Efficacy, Safety and Suitability of Disinfectants to Prevent Emerging Infectious Disease Transmission. Water 10 (10), 1397.

Lantagne D, Rayner J, Mittelman A, and Pennell K (2017). Comment on "A re-assessment of the safety of silver in household water treatment: rapid systematic review of mammalian in vivo genotoxicity studies" Environmental Health 16:121.

Murray A
, Kumpel E, Peletz R, Khush R, and Lantagne D (2017). The effect of sodium thiosulfate dechlorination on fecal indicator bacteria enumeration: laboratory and field data. Journal of Water and Health. DOI: 10.2166/wh.2017.077.

Wilhelm N, Kaufmann A, Blanton E, and Lantagne D (2017). Sodium hypochlorite dosage for household and emergency water treatment: updated recommendations. Journal of Water and Health DOI: 10.2166/wh.2017.012.

Wolfe M and Lantagne D (2017). A method to test the efficacy of handwashing for the removal of emerging infectious pathogens. Journal of Visual Experiments Jun 7(124). DOI: 10.3791/55604.

Gallandat K and Lantagne D (2017). Selection of a Biosafety Level 1 (BSL-1) surrogate to evaluate surface disinfection efficacy in Ebola outbreaks: Comparison of four bacteriophages. PLoS ONE 12(5): e0177943.

Rayner J, Luo X, Schubert J, Lennon P, Jellison K, and Lantagne D (2017). The effects of input materials on ceramic water filter efficacy for household drinking water treatment. Water Science and Technology: Water Supply 17(3): 859-869.

Gallandat K, Wolfe M, and Lantagne D (2017). Surface cleaning and disinfection: Efficacy assessment of four chlorine types using Escherichia coli and the Ebola Surrogate Phi6. Environmental Science & Technology 51(8): 4624-4631.

Murray A, Steward B, Hopper C, Tobin E, Rivera J, Mut-Tracy H, Stewart P, Stewart C, Tobin C,
Goeb M, Meub C, and Lantagne D (2017). Laboratory efficacy and field effectiveness of hollow fiber membrane microfilters used for household water treatment in Honduras. Journal of Water, Sanitation, and Hygiene for Development 7(1): 74-84.

Wolfe M, Gallandat K, Daniels K, Desmarais AM, Scheinman P, and Lantagne D (2017). Handwashing and Ebola virus disease outbreaks: A randomized comparison of soap, hand sanitizer, and 0.05% chlorine solutions on the inactivation and removal of model organisms Phi6 and E. coli from hands and persistence in rinse water. PLoS ONE 12(2): e0172734.

Meade R, Murray A, Mittelman A, Rayner J, and Lantagne D (2017). Accuracy, precision, usability, and cost of portable silver test methods for ceramic filter factories. Journal of Water and Health 15(1): 72-82.

Wolfe M, Wells E, Mitro B, Desmarais A, Scheinman P, and Lantagne D (2017). Seeking clearer recommendations for hand hygiene in communities facing Ebola: A randomized trial investigating the impact of six handwashing methods on skin irritation and dermatitis. PLoS ONE 11(12): e0167378.

Murphy J, Ayers T, Knee J, Oremo J, Odhiambo A, Faith S, Nyagol R, Stauber C, Lantagne D, and Quick R. (2016). Evaluating four measures of water quality in clay pots and plastic safe storage containers in Kenya. Water Research. 104: 312-319.

Iqbal Q, Lubeck-Schricker M, Wells E, Wolfe M, and Lantagne D (2016). Shelf-life of chlorine solutions recommended in Ebola virus disease response. PLoS ONE 11(5): e0156136.

Wells E, Wolfe M, Murray A, and Lantagne D (2016). Accuracy, precision, ease-of-use, and cost of methods to test Ebola-relevant chlorine solutions. PLoS ONE 11(5): e0152442.

Mittelman AM, Lantagne DS, Rayner J, and Pennell KD (2015). Silver dissolution and release from ceramic water filters. Environmental Science and Technology 49(14): 8515-22.

Lantagne DS and Hunter PR (2015). Comment on "Ebola virus persistence in the environment: state of the knowledge and research needs". Environmental Science & Technology Letters 2(2): 48-49.

Lantagne D (2015). Comment on "Household effectiveness vs. laboratory efficacy of point-of-use chlorination". Water Research 69: 328-30.

Lantagne D, Person B, Smith N, Mayer A, Preston K, Blanton E, and Jellison K (2014). Emergency water treatment with bleach in the United States: the need to revise EPA recommendations. Environmental Science & Technology 48(9): 5093-5100.

Murray A and Lantagne D (2015). Accuracy, precision, usability, and cost of free chlorine residual testing methods. J Water Health 13(1), 79-90.

Rayner J, Zhang H, Schubert J, Lennon P, Lantagne D, and Oyanedel-Craver V (2013). Laboratory investigation into the effect of silver applied on the bacteriological removal efficacy of filter material for use on locally-produced ceramic water filters for household drinking water treatment. ACS Sustainable Chemistry & Engineering 1(7), 737-745.