About the Lab


The Diffuse Optical Imaging of Tissue (DOIT) lab includes faculty, postdocs, Ph.D. students, M.S. students, and undergraduate students who perform independent research studies, lab rotations, or summer internships. We hold weekly group meetings, including regular joint research meeting with our collaborating groups.

Diffuse optical imaging is a non-invasive technique for low-resolution studies of biological tissues at a macroscopic scale. The limited spatial resolution (~10 mm) is balanced by a large optical penetration depth (tens of millimeters), high temporal resolution (tens of milliseconds), high intrinsic contrast associated with hemoglobin, and the capability of spectral discrimination of multiple chromophores (leading to quantitative oximetry in the case of oxygenated and deoxygenated hemoglobin).

Research activities in our group include quantitative modeling of light propagation in optically turbid media, the generation of analytical relationships between optical measurements and physiological quantities, the design of optical instruments for medical imaging, the development of novel near-infrared spectroscopy and imaging techniques for medical diagnostics, and a number of applications human subjects. Specific applications are aimed at functional imaging of the brain, the assessment of cerebral microcirculation, hemodynamic monitoring of skeletal muscles, and quantitative tissue oximetry.

We attend major scientific conferences in the field, such as SPIE Photonics West BiOS and the Optica Biophotonics Congress. We also actively participate in many of the social activities organized by the department, which include the Tufts Optics Research club meetings, the annual Biomedical Engineering retreat, and the summer department picnic.

We hope that you enjoy our group website and we encourage you to contact us for any questions.

Twitter: https://twitter.com/TuftsDOIT/

GitHub: https://github.com/DOIT-Lab/DOIT-Public/

Learn about our research