Department of Chemical and Biological Engineering
Van Deventer Lab
Van Deventer Lab

Publications

At Tufts

  1. Stieglitz, J. T.; Lahiri, P.; Stout, M. I.; Van Deventer, J. A. Exploration of Methanomethylophilus alvus pyrrolysyl-tRNA synthetase activity in yeast. bioRxiv 2022, 2022.01.07.475408; doi: https://doi.org/10.1101/2022.01.07.475408
  2. Hershman, R. L.; Li, Y.; Ma, F.; Xu, Q.; Van Deventer, J. A. Intracellular Delivery of Antibodies for Selective Cell Signaling Interference. ChemMedChem 2022, e202100678. 
  3. Stieglitz, J. T.; Van Deventer, J. A. High-throughput aminoacyl-tRNA synthetase engineering for genetic code expansion in yeast. bioRxiv 2021, 2021.07.13.452272; doi: https://doi.org/10.1101/2021.07.13.452272
  4. Stieglitz, J. T.; Potts, K. A.; Van Deventer, J. A. Broadening the Toolkit for Quantitatively Evaluating Noncanonical Amino Acid Incorporation in Yeast. ACS Synthetic Biology 2021, 10 (11), 3094-3104.  
  5. Lei, M.; Jayaraman, A.; Van Deventer, J. A.; Lee, K. Engineering Selectively Targeting Antimicrobial Peptides. Annual Review of Biomedical Engineering 2021, 23 (1), 339-257. 
  6. Van Deventer, J. A. Liven Up That Linker. Journal of Medicinal Chemistry 2021, 64 (5), 2521-2522. 
  7. Lei, M.; Trivedi, V. D.; Nair, N. U.; Lee, K.; Van Deventer, J. A. Flow Cytometric Evaluation of Yeast-Bacterial Cell-Cell Interactions. bioRxiv 2021, 10.13.464218; doi: https://doi.org/10.1101/2021.10.13.464218. 
  8. Van Deventer, J. A. Desperately seeking sortase. Nature Chemical Biology 2021, 17, 235-236. 
  9. Islam, M.; Kehoe, H. P.; Lissoos, J. B.; Huang, M.; Ghadban, C. E.; Berumen Sánchez, G.; Lane, H. Z.; Van Deventer, J. A., Chemical Diversification of Simple Synthetic Antibodies. ACS Chemical Biology 2021, 16 (2), 344-359.
  10. Potts, K.P., Stieglitz, J.T., Lei, M., and Van Deventer, J.A.*, “Reporter system architecture affects measurements of noncanonical amino acid incorporation efficiency and fidelity.” Mol. Syst. Des. Eng., 2020, 5, 573-588. *Corresponding author.
  11. Rezhdo, A., Islam, M., Huang, M., and Van Deventer, J.A.*, “Future prospects for noncanonical amino acids in biological therapeutics.” Curr. Opin. Biotechnol., 2019, 60, 168-178. *Corresponding author.
  12. Stieglitz, J.T., Kehoe, H.P., Lei, M., and Van Deventer, J.A.* "A robust and quantitative reporter system to evaluate noncanonical amino acid incorporation in yeast." ACS Synth. Biol., 2018, 7, 2256–2269.
    *Corresponding author.

Transitional (started at MIT, completed at Tufts)

  1. Van Deventer, J.A.*, Le, D.N., Zhao, J., Kehoe, H.P., and Kelly, R.L. "A platform for constructing, evaluating, and screening bioconjugates on the yeast surface." Protein Eng. Des. Sel. 2016, 29, 485-494. *Corresponding author.

Additional publications

  1. Li, X., Van Deventer, J. A., Hassoun, S., “ASAP-SML: An antibody sequence analysis pipeline using statistical testing and machine learning.” PLoS Comput Biol, 2020, 16, 4.
  2. Hwang, S.S., Chan, H., Sorci, M., Van Deventer, J., Wittrup, D., Belfort, G., Walt, D., “Detection of amyloid beta oligomers toward early diagnosis of Alzheimer's disease.” Anal. Biochem. 2019, 566, 40-45.
  3. Van Deventer, J.A.*,†, Kelly, R.L.†, Rajan, S., Wittrup, K.D., and Sidhu, S.S.* "A switchable yeast display/secretion system." Protein Eng. Des. Sel. 2015, 28, 317-325. *Corresponding author. †Equal contributions.
  4. Angelini, A., Chen, T.F., de Picciotto, S., Yang N.J., Tzeng, A., Santos, M.S., Van Deventer, J.A., Traxlmayr, M.W., Wittrup, K.D. "Protein engineering and selection using yeast surface display." Methods Mol. Biol. 2015, 1319, 3-36.
  5. Van Deventer, J.A., Yuet, K.P., Yoo, T.H., Tirrell, D.A. "Cell surface display yields evolvable, clickable antibody fragments." ChemBioChem 2014, 15, 1777–1781.
  6. Van Deventer, J.A., Wittrup, K.D. "Yeast surface display for antibody isolation: library construction, library screening, and affinity maturation," Methods Mol. Biol. 2014, 1131, 151-181.
  7. Van Deventer, J.A., Fisk, J.D., and Tirrell, D.A. "Homoisoleucine: a translationally active leucine surrogate of expanded hydrophobic surface area." ChemBioChem 2011, 12, 700-702.
  8. Kwon, O.-H., Yoo, T.H., Othon, C.M., Van Deventer, J.A., Tirrell, D.A., and Zewail, A.H. "Hydration dynamics at fluorinated protein surfaces." Proc. Natl. Acad. Sci. USA 2010, 107, 17101-17106.
  9. Johnson, J.A., Lu, Y.Y., Van Deventer, J.A., Tirrell, D.A. "Residue-specific incorporation of non-canonical amino acids into proteins: recent developments and applications." Curr. Opin. Chem. Biol. 2010, 14, 774-780.
  10. Tang, Y., Wang, P., Van Deventer, J.A., Link, A.J., Tirrell, D.A. "Introduction of an aliphatic ketone into recombinant proteins in a bacterial strain that overexpresses an editing-impaired leucyl-tRNA synthetase." ChemBioChem 2009, 10, 2188-2190.
  11. Filler, M.A., Van Deventer, J.A., Keung, A.J., and Bent, S.F. "Carboxylic acid chemistry at the Ge(100)-2x1 interface: bidentate bridging structure formation on a semiconductor surface." J. Am. Chem. Soc. 2006, 128, 770-779.