Research/Areas of Interest
Drug product development for therapeutic proteins. Application of biophysical and thermodynamic approaches to formulation development. Physical and chemical stability of proteins, ligand binding and linkage. Drug-device integration.
Education
- PhD in chemistry/biochemistry, University of Missouri, United States
Biography
Bernardo Perez-Ramirez is a Senior Scientific Director and Global Head of CMC-Drug Device Integration at Sanofi. His current responsibilities include scientific and strategic advice on CMC-Drug Device integration. He has more than twenty-five years of experience in the biopharmaceutical industry in particular in formulation and drug product development for therapeutic proteins (enzyme, monoclonal antibodies, agonists, growth factors, combination products and gene therapy) including drug device integration and technology transfer. Prior to his tenure at Sanofi/Genzyme, he spent eight years at Genetics institute/Wyeth (now Pfizer) where he was responsible for formulation of implantable combination products and implementation of device controls for biologic products. He received his PhD in chemistry/biochemistry from the University of Missouri and did postdoctoral research on physical biochemistry of proteins at Brandeis University. He has been an active participant in different focus scientific groups and co-organizer of conferences, giving lectures at different universities within the US and Europe. Honorary Professor of Formulation & Drug Product Development, School of BioSciences at the University of Nottingham-United Kingdom. Member of the American Society for Biochemistry and Molecular Biology (US); elected fellow of the Royal Society of chemistry and the Royal Society of Arts (England).