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Department of Biomedical Engineering

Barbara Brodsky

Research Professor

Barbara Brodsky

Research Professor

Phone 617-627-0447
Science and Technology Center, Room 125
4 Colby Street, Medford, MA
Research: 
biophysics, collagen, protein structure
Biography: 

Barbara Brodsky earned her B.A. in physics from Brandeis University in 1964 and her Ph.D. in biophysics from Harvard University in 1970, after which she carried out postdoctoral research as a Helen Hay Whitney Fellow at NIH and Oxford University, UK. From 1975-2010, she served on the faculty of the department of biochemistry at Robert Wood Johnson Medical School, affiliated with Rutgers University, ultimately achieving the rank of professor and position of deputy chair while maintaining continuous NIH funding for her collagen research. In 2010, she joined the Tufts Department of Biomedical Engineering as a research professor.

Education: 
Ph.D., Biophysics, Harvard University, 1970
B.A., Physics, Brandeis University, 1964
Research Interests: 

Barbara Brodsky's research focuses on collagen, an extracellular matrix component critical for tissue structure, mechanical properties, cell adhesion and receptor mediated cell signaling. She characterizes structural features of collagen using model peptides and a recently developed recombinant bacterial collagen. The recombinant molecules serve as an excellent model system for defining collagen binding sites and the effects of collagen mutations, while the peptides allow definition of high resolution features at biologically important sites. Research is currently underway to clarify the pathway from human collagen mutations to hereditary bone disorders, kidney disease, and vascular pathology. Studies are being initiated to utilize the recombinant collagen system as a scaffold to promote bone generation by human stem cells and for the development of biomaterials.

Selected Honors and Awards: 
  • 2013: Elected Fellow, American Association for the Advancement of Science (AAAS)
  • 2009: Professor Richard A. Harvey Excellence in Teaching Innovation Award, Rutgers Medical School
  • 2006: Thomas Alva Edison Patent Award
  • 1976: NIH Research Career Development Award
  • 1972: Helen Hay Whitney Postdoctoral Fellowship
Selected Professional Activities: 
Member, Editorial Board, Journal of Biological Chemistry
Editor, Newsletter International Society of Matrix Biology
Member, Council, International Society of Matrix Biology
Professional Memberships: 
American Society of Biochemistry and Molecular Biology
American Chemical Society
Biophysical Society
Protein Society
International Society of Matrix Biology
American Association for the Advancement of Science